Molecular Basis of Inheritance

Types of RNA

Atomic RNA Dossier | BSI Style The RNA World Dossier Types, Enzymes & Cellular Secrets…

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The Atomic History of DNA-A Chronological Dossier

The Atomic History of DNA | BSI Style BSI SIR Presents DNA HISTORY – A…

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A gene is defined as the functional unit of inheritance.The DNA sequence coding for tRNA or rRNA molecule also define a gene.Inheritance of a character is also affected by promoter and regulatory sequences of a structural gene. Hence, sometime the regulatory sequences are loosely defined as regulatory genes, even though these sequences do not code for any RNA or protein. The DNA sequence coding for tRNA or rRNA molecule also define a gene

What is a Gene? A gene is the functional unit of inheritance. It carries the…

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Bacteria like E. coli divide every 20 minutes. But their DNA — about 4.6 million base pairs — takes about 38 minutes to replicate at 2000 base pairs per second. So how do they manage it?

🧬 The DNA-Time Dilemma Bacteria like E. coli divide every 20 minutes. But their DNA…

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MOLECULAR BASIS OF INHERITANCE -1- Over the next hundred years, the nature of the putative genetic material was investigated culminating in the realisation that DNA – deoxyribonucleic acid – is the genetic material, at least for the majority of organisms.

Master Table: Molecular Basis of Inheritance Topic Explanation Key Details MCQ Inheritance Patterns Factors regulating…

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During replication and transcription a nucleic acid was copied to form another nucleic acid. Hence, these processes are easy to conceptualise on the basis of complementarity. The process of translation requires transfer of genetic information from a polymer of nucleotides to synthesise a polymer of amino acids. Neither does any complementarity exist between nucleotides and amino acids, nor could any be drawn theoretically. There existed ample evidences, though, to support the notion that change in nucleic acids (genetic material) were responsible for change in amino acidsin proteins. This led to the proposition of a genetic code that could directthe sequence of amino acids during synthesis of proteins.

Concept Description Genetic Code The set of rules by which information encoded in genetic material…

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The split-gene arrangements represent probably an ancientfeature of the genome. The presence of introns is reminiscent of antiquity,and the process of splicing represents the dominance of RNA-world. In recent times, the understanding of RNA and RNA-dependent processes in the living system have assumed more importance.

Aspect Description Distinguishing RNA Subsets In early cells that lacked DNA, a crucial problem was…

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NCERT-NEET-An intriguing question is that how is the RNA polymerases able to catalyse all the three steps, which are initiation, elongation and termination. The RNA polymerase is only capable of catalysing the process of elongation. It associates transiently with initiation-factor (σ)and termination-factor (ρ) to initiate and terminate the transcription, respectively. Association with these factors alter the specificity of theRNA polymerase to either initiate or terminate

Feature Description Definition The process of copying genetic information from one strand of DNA into…

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DNA Replication – The Machinery and the Enzymes -NCERT-NEET-‘‘It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material’’(Watson and Crick, 1953).

Step Enzymes Involved Details Prokaryotic vs Eukaryotic Differences Initiation Helicase, Primase Helicase unwinds the DNA…

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